For research and laboratory use only. Not for human or veterinary consumption.

This product is sold for research purposes only. It is not intended for human consumption, diagnosis, treatment, cure, or prevention of any disease. Purchaser acknowledges that this material is for laboratory research use only.

Biology, Structural

99.5% Purity

10mg lyophilized vial

KPV

“A 3-amino acid tripeptide (Lys-Pro-Val) derived from the C-terminus of alpha-melanocyte-stimulating hormone that inhibits NF-κB activation via PepT1-mediated cellular uptake in preclinical inflammatory research models. Premium Research Peptide.

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🧪

Compound Information

Technical specifications

🔬 Molecular Profile

What Is KPV?

Type
Synthetic tripeptide
Sequence
Lys-Pro-Val (KPV)
Amino acids
3
Molecular formula
C₁₆H₃₀N₄O₄
Molecular weight
342.43 g/mol
CAS Number
67727-97-3
Origin
α-MSH residues 11-13

🧬 Parent Compound

Relationship to α-MSH

Parent peptide
α-Melanocyte-Stimulating Hormone
α-MSH length
13 amino acids
KPV position
C-terminal (11-13)
Activity retained
Anti-inflammatory effects
MCR binding
NOT required for activity

🧊 Storage Requirements

Stability Information

Freeze for storage Refrigerate after reconstitution Protect from light

Lyophilized (powder)
-20°C long-term
Reconstituted
2-8°C • use within 7 days
Light protection
Store away from light

📚

Sources & References

Peer-reviewed research

Gastroenterology
PepT1-Mediated Tripeptide KPV Uptake Reduces Intestinal Inflammation
2008 • DOI: 10.1053/j.gastro.2007.10.026 • PMID: 18061177 Dalmasso G, Charrier-Hisamuddin L, Nguyen HT, et al.
British Journal of Pharmacology
α-MSH Related Peptides: A New Class of Anti-Inflammatory and Immunomodulating Drugs
2000 • DOI: 10.1111/j.1476-5381.2000.00178.x Luger TA, Brzoska T, Scholzen TE, et al.
Molecular Pharmaceutics
Orally Targeted Delivery of Tripeptide KPV via Hyaluronic Acid-Functionalized Nanoparticles Efficiently Alleviates Ulcerative Colitis
2017 • PMID: 28548842 Xiao B, Xu Z, Viennois E, et al.
Annals of the New York Academy of Sciences
Melanocortin-Derived Tripeptide KPV Has Anti-Inflammatory Potential in Murine Models of Inflammatory Bowel Disease
2008 • PMID: 18226903 Kannengiesser K, Maaser C, Heidemann J, et al.
Journal of Investigative Dermatology
Alpha-Melanocyte-Stimulating Hormone and Related Tripeptides: Biochemistry, Antiinflammatory and Protective Effects
1999 Brzoska T, Luger TA, Maaser C, et al.

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Certificate of Analysis

Researcher verification

Elev-8 Labs sells research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Please confirm before continuing.

By proceeding, you affirm the statements above are true: products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.