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For research and laboratory use only. Not for human or veterinary consumption.

5-Amino-1MQ

This product is sold for research purposes only. It is not intended for human consumption, diagnosis, treatment, cure, or prevention of any disease. Purchaser acknowledges that this material is for laboratory research use only.

Biochemical

99.4% Purity

50mg lyophilized vial

5-Amino-1MQ

A selective small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT) that modulates NAD+ salvage and lipogenesis pathways in preclinical metabolic research models. Premium Research Peptide.

Quantity
$69.99 Bundle price $69.99
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Compound Information

Technical specifications

🔬 Molecular Profile

What Is 5-Amino-1MQ?

Type
Small molecule NNMT inhibitor
CAS Number
42464-96-0
Molecular Weight
159.21 g/mol (cation)
Salt Form
286.11 g/mol (iodide salt)
Formula
C₁₀H₁₁N₂⁺ (cation)
Appearance
Brown to reddish-brown solid

🧊 Storage Requirements

Stability Information

Lyophilized (powder)
-20°C • stable 24+ months
Short-term storage
2-8°C • up to 30 days
Reconstituted
2-8°C • use within 7-14 days

📚

Sources & References

Peer-reviewed research

Journal of Medicinal Chemistry
Structure-Activity Relationship for Small Molecule Inhibitors of Nicotinamide N-Methyltransferase
2017 • DOI: 10.1021/acs.jmedchem.7b00389 • PMID: 28548833 Neelakantan H, Wang HY, Vance V et al.
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Biochemical Pharmacology
Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice
2018 • DOI: 10.1016/j.bcp.2017.11.007 • PMID: 29155147 Neelakantan H, Vance V, Wetzel MD et al.
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Biochemical Pharmacology
Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle
2019 • DOI: 10.1016/j.bcp.2019.02.008 • PMID: 30753815 Neelakantan H, Brightwell CR, Graber TG et al.
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Scientific Reports
Combined nicotinamide N-methyltransferase inhibition and reduced-calorie diet normalizes body composition and enhances metabolic benefits in obese mice
2021 • DOI: 10.1038/s41598-021-85051-6 • PMID: 33707534 Sampson CM, Dimet AL, Neelakantan H et al.
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Journal of Pharmaceutical and Biomedical Analysis
Development & validation of LC-MS/MS assay for 5-amino-1-methyl quinolinium in rat plasma: Application to pharmacokinetic and oral bioavailability studies
2021 • DOI: 10.1016/j.jpba.2021.114255 • PMID: 34304009 Awosemo O, Neelakantan H, Watowich S et al.
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Journal of Obstetrics and Gynaecology
Small molecule inhibitor of nicotinamide N-methyltransferase shows anti-proliferative activity in HeLa cells
2021 • DOI: 10.1080/01443615.2020.1854696 • PMID: 33645410 Akar S, Duran T, Azzawri AA et al.
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Scientific Reports
Reduced calorie diet combined with NNMT inhibition establishes a distinct microbiome in DIO mice
2022 • DOI: 10.1038/s41598-021-03670-5 • PMID: 35013352 Dimet-Wiley A, Wu Q, Wiley JT et al.
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Diabetes, Obesity and Metabolism
Nicotinamide N-methyltransferase inhibition mitigates obesity-related metabolic dysfunction
2024 • DOI: 10.1111/dom.15879 • PMID: 39161060 Babula JJ, Bui D, Stevenson HL et al.
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Researcher verification

Elev-8 Labs sells research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Please confirm before continuing.

By proceeding, you affirm the statements above are true: products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.