For research and laboratory use only. Not for human or veterinary consumption.

This product is sold for research purposes only. It is not intended for human consumption, diagnosis, treatment, cure, or prevention of any disease. Purchaser acknowledges that this material is for laboratory research use only.

Cellular

99.5% Purity

10mg lyophilized vial

Epithalon

Epithalon — synthetic tetrapeptide (Ala-Glu-Asp-Gly). CAS 307297-39-8 · MW 390.35 g/mol · 99.5% purity · Store at –20°C up to 2 years; reconstituted, 2–8°C up to 30 days.

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Compound Information

Technical specifications

Molecular Profile

🔬 Molecular Profile

What Is Epithalon?

Type
Synthetic tetrapeptide
CAS Number
307297-39-8
Molecular Weight
390.35 g/mol
Amino Acids
4 (tetrapeptide)
Sequence
Ala-Glu-Asp-Gly (AEDG)
Formula
C₁₄H₂₂N₄O₉

🧊 Storage Requirements

Stability Information

Protect from light Avoid repeated freeze-thaw Store in original sealed vial

Lyophilized (powder)
-20°C • up to 2 years
Reconstituted
2-8°C • up to 30 days

📚

Sources & References

Peer-reviewed research

International Journal of Molecular Sciences
Overview of Epitalon — Highly Bioactive Pineal Tetrapeptide with Promising Properties 2025 • DOI: 10.3390/ijms2
2025 • DOI: 10.3390/ijms26062691 • PMID: 40141333 Araj SK, Brzezik J, Mądra-Gackowska K, Szeleszczuk Ł
Bulletin of Experimental Biology and Medicine
Epithalon Peptide Induces Telomerase Activity and Telomere Elongation in Human Somatic Cells
2003 • DOI: 10.1023/a:1025493705728 • PMID: 12937682 Khavinson VK, Bondarev IE, Butyugov AA
Bulletin of Experimental Biology and Medicine
Peptide Promotes Overcoming of the Division Limit in Human Somatic Cells
2004 • DOI: 10.1023/b:bebm.0000038164.49947.8c • PMID: 15455129 Khavinson VKh, Bondarev IE, Butyugov AA
Bulletin of Experimental Biology and Medicine
Effect of Peptide AEDG on Telomere Length and Mitotic Index of PHA-Stimulated Human Blood Lymphocytes
2019 • DOI: 10.1007/s10517-019-04664-0 Khavinson VKh, Pendina AA, Efimova OA, et al.
Molecules
AEDG Peptide (Epitalon) Stimulates Gene Expression and Protein Synthesis during Neurogenesis: Possible Epigenetic Mechanism
2020 • DOI: 10.3390/molecules25030609 • PMID: 32019204 Khavinson V, Diomede F, Mironova E, et al.
Mechanisms of Ageing and Development
Effect of Epitalon on the Lifespan Increase in Drosophila melanogaster
2000 Khavinson VKh, Izmaylov DM, Obukhova LK, Malinin VV
Mechanisms of Ageing and Development
Effect of Synthetic Thymic and Pineal Peptides on Biomarkers of Ageing, Survival and Spontaneous Tumour Incidence in Female CBA Mice
2001 Anisimov VN, Khavinson VKh, Mikhalski AI, Yashin AI
Bulletin of Experimental Biology and Medicine
Regulatory Effect of Epithalon on Production of Melatonin and Cortisol in Old Monkeys
2001 Goncharova ND, Khavinson BK, Lapin BA
International Journal of Cancer
Inhibitory Effect of the Peptide Epitalon on the Development of Spontaneous Mammary Tumors in HER-2/neu Transgenic Mice
2002 • PMID: 12209581 Anisimov VN, Khavinson VKH, Provinciali M, et al.
Journal of Restorative Medicine
Improving Biological Age, Telomere Length, and Cognition: A Case Study
2024 Published case report
Bulletin of Experimental Biology and Medicine
Molecular Cellular Mechanisms of Peptide Regulation of Melatonin Synthesis in Pinealocyte Culture
2012 Khavinson VK, Linkova NS, Kvetnoy IM, et al.
Advances in Gerontology
AEDG Peptide Prevents Oxidative Stress in the Model of Induced Aging of Skin Fibroblasts
2022 Gutop EO, Linkova NS, Kozhevnikova EO, et al.

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Certificate of Analysis

Researcher verification

Elev-8 Labs sells research peptides exclusively to qualified researchers and laboratories for in vitro and laboratory use. Please confirm before continuing.

By proceeding, you affirm the statements above are true: products are not for human or veterinary use, not for use in diagnostic procedures, and have not been evaluated by the U.S. Food and Drug Administration.